Native Plants and Ancient Wisdom Spark Groundbreaking Medical Breakthroughs

Quick Smiles:

• Scientists at the Salk Institute are teaming up with Native Americans to explore the medicinal potential of California’s native plants.
• Plants like ephedra, artemisia, and yerba santa are being studied for their roles in treating illnesses such as syphilis, asthma, and even Alzheimer’s disease.
• The project aims to create a “circular ecosystem” that benefits both tribal nations and the environment.

Researchers at the prestigious Salk Institute for Biological Studies in San Diego are uncovering the secrets of native California plants, working hand in hand with Native American communities. Their goal? To transform traditional herbal remedies into modern medicines that could address everything from syphilis to neurological disorders.

At the Medicinal Plants Nursery in the San Diego Botanic Garden, scientists are delving into the genetic makeup of these plants, many of which have been used for centuries by Indigenous peoples. Dr. Todd Michael, a biologist at Salk, explained the fascinating relationship between humans and these plants:

“We have co-evolved with all of these medicinal plants,” he said.

“I mean, they make these things probably to protect themselves, but also maybe because they make their mammal counterparts happy.”

One of the plants under study is ephedra, known for its historical use in treating syphilis, weight loss, allergies, asthma, and headaches. Another is artemisia, long used as a remedy for malaria. Yerba santa, a plant traditionally used by Native Americans, has caught the attention of researchers for its potential as a key ingredient in a neurological drug for Alzheimer’s disease.

The collaboration between Salk scientists and tribal nations is more than just a scientific endeavor—it’s a partnership rooted in mutual respect and shared knowledge. Native communities are contributing their expertise on the plants’ traditional uses, while researchers apply cutting-edge science to uncover new possibilities.

The project is gaining recognition across the country. Nurseries and research institutions nationwide are sending seeds, cuttings, and plants to support the effort. This growing interest highlights the potential for these plants to revolutionize medicine.

Dr. Ben Neiman, another scientist involved in the project, sees a broader vision for the work. He describes the potential economic and environmental benefits as a “circular ecosystem.”

“The more drugs that can be developed,” he explained, “the more that tribal nations in and around San Diego County, and the natural landscape where these plants thrive, can be rewarded and protected.”

This innovative research not only shines a light on the healing power of nature but also emphasizes the importance of preserving the ecosystems and cultural knowledge that make these discoveries possible.

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